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Tissue distribution of blood group membrane proteins beyond red cells: evidence from cDNA libraries.

机译:红细胞以外的血型膜蛋白的组织分布:来自cDNA文库的证据。

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摘要

The proteins of blood group systems are expressed on red blood cells (RBC) by definition. We searched nucleotide databases of human expressed sequence tags (EST) to collate the distribution of 22 distinct membrane proteins in cells and tissues other than RBC. The documented blood group genes are: MNS, Rh, Lutheran, Kell, Duffy, Kidd, Diego, Yt, Xg, Scianna, Dombrock, Colton, Landsteiner-Wiener, Kx, Gerbich, Cromer, Knops, Indian, Ok, Raph, John-Milton-Hagen and Gill. The genes were grouped according to their overall and their relative expression in embryo and adults. We describe the distribution of EST in cells, tissues and cell lines with a focus on non-RBC tissues.
机译:根据定义,血型系统的蛋白质在红细胞(RBC)上表达。我们搜索了人类表达的序列标签(EST)的核苷酸数据库,以整理22种不同膜蛋白在RBC以外的细胞和组织中的分布。记录的血型基因是:MNS,Rh,路德教会,凯尔,达菲,基德,迭戈,Yt,Xg,席安纳,唐布罗克,科尔顿,Landsteiner-Wiener,Kx,格比希,克罗默,诺普斯,印度人,好-Milton-Hagen和Gill。根据基因的整体及其在胚胎和成年中的相对表达将基因分组。我们描述了EST在细胞,组织和细胞系中的分布,重点是非RBC组织。

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