Real-time ultrasound-guided central venous catheterization reduces the need for prophylactic platelet transfusion in thrombocytopenic patients with hematological malignancy

摘要

Platelet transfusion is usually recommended in case of invasive procedures. Prophylactic platelet transfusion is indicated for patients with a platelet count of <50 x 109/L [1,2]. Patients with thrombocytopenic disorders require preprocedural platelet transfusion before undergoing central vein catheterization. However, despite prior platelet transfusion, even with experienced operators, bleeding complication rates of up to 15% have been reported after central vein catheterization by the conventional landmark technique in patients with a platelet count of <20 x 109/L [3]. On the contrary, real-time ultrasound-guided central vein catheterization is found to have a high success rate, and it dramatically reduces the complications [4,5]. We aimed to compare success rates, complications, and prophylactic platelet transfusion requirement between realtime ultrasound-guided central venous catheterization and central venous catheterization by the landmark technique.