Multiple changes in oncogenes and tumor suppressor genes in human retinoblastoma.

Howard RO

首页> 外文期刊>Transactions of the American Ophthalmological Society. >Multiple changes in oncogenes and tumor suppressor genes in human retinoblastoma.

【24h】

Multiple changes in oncogenes and tumor suppressor genes in human retinoblastoma.

机译：人类视网膜母细胞瘤中癌基因和抑癌基因的多重变化。

获取原文

获取原文并翻译 | 示例

获取外文期刊封面封底 >>

开具论文收录证明 >>

文献代查 >>

团队文献服务 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

PURPOSE: To present data to support the hypothesis that human retinoblastoma tumors form by a multistep process. METHODS: Survey of the karyotype of 90 human retinoblastomas, with emphasis on changes in chromosomal regions known to contain oncogenes and tumor suppressor genes. CONCLUSION: The data support the hypothesis that retinoblastoma occurs after multiple and often varied steps, similar to other human malignancies.

机译：目的：提供数据以支持人视网膜母细胞瘤肿瘤是由多步过程形成的假说。方法：对90例人类视网膜母细胞瘤的核型进行了调查，重点研究了已知含有癌基因和抑癌基因的染色体区域的变化。结论：数据支持这样的假说，即成视网膜细胞瘤发生于多个且通常是不同的步骤之后，类似于其他人类恶性肿瘤。

著录项

来源
《Transactions of the American Ophthalmological Society. 》 |1996年第0期| 共16页
作者
Howard RO;
展开▼
作者单位

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类眼科学 ;
关键词
Eye Neoplasms; Genes; Tumor Suppressor genetics; Genes; ras; Retinoblastoma; 眼肿瘤; 基因; RAS; 视网膜母细胞瘤;

机译：Eye Neoplasms;Genes;Tumor Suppressor genetics;Genes;ras;Retinoblastoma;眼肿瘤;基因;RAS;视网膜母细胞瘤;

相似文献

外文文献
中文文献
专利

1. Multiple changes in oncogenes and tumor suppressor genes in human retinoblastoma. [J] . Howard RO Transactions of the American Ophthalmological Society. . 1996 ,第0期

机译：人类视网膜母细胞瘤中癌基因和抑癌基因的多重变化。
2. Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Caspases; Catechin; Cell Line, Tumor; Ceramides; Drug Synergism; Enzyme Activation; Humans; Ibuprofen; Male; Mitogen-Activated Protein Kinases; Oxidative Stress; Phosphorylation; Prostatic Neoplasms; Proto-Oncogene Proteins c-bcl-2; Tumor Suppressor Protein p53;*脱噬作用; Caspase类; 儿茶素; 神经酰胺类; 药物协同作用; 酶激活; 布洛芬; 氧化性应激; 磷酰化; 前列腺肿瘤; 原致癌基因蛋白质 c-bcl-2 [J] . The Netherlands journal of medicine. . 2009 ,第6期

机译：Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Caspases; Catechin; Cell Line, Tumor; Ceramides; Drug Synergism; Enzyme Activation; Humans; Ibuprofen; Male; Mitogen-Activated Protein Kinases; Oxidative Stress; Phosphorylation; Prostatic Neoplasms; Proto-Oncogene Proteins c-bcl-2; Tumor Suppressor Protein p53;*脱噬作用; Caspase类; 儿茶素; 神经酰胺类; 药物协同作用; 酶激活; 布洛芬; 氧化性应激; 磷酰化; 前列腺肿瘤; 原致癌基因蛋白质 c-bcl-2
3. KRAB zinc finger protein ZNF382 is a proapoptotic tumor suppressor that represses multiple oncogenes and is commonly silenced in multiple carcinomas. [J] . Cheng Y, Geng H, Cheng SH, Cancer research: The official organ of the American Association for Cancer Research, Inc . 2010 ,第16期

机译：Krab锌指蛋白ZNF382是一种抑制多种癌基因的促凋亡肿瘤抑制剂，通常在多个癌中沉默。
4. Oncogenes and tumor suppressor genes in murine tumors induced by neutron- or gamma-irradiation in utero [C] . Sara Antal, K. Lumniczky, J. Palfalvi, International Symposium of Radiation and Homeostasis . 2002

机译：子宫中子或γ-辐照诱导的鼠肿瘤中的癌肠和肿瘤抑制基因
5. Mechanisms of inactivation of multiple tumor suppressor genes in human prostate cancer. [D] . Gao, Xiang. 1997

机译：人类前列腺癌中多种肿瘤抑制基因失活的机制。
6. Multiple changes in oncogenes and tumor suppressor genes in human retinoblastoma. [O] . R O Howard 1996

机译：人视网膜母细胞瘤中癌基因和抑癌基因的多重变化。
7. KRAB zinc finger protein ZNF382 is a proapoptotic tumor suppressor that represses multiple oncogenes and is commonly silenced in multiple carcinomas [O] . Fukagawa, T, Wu, X, Chan, ATC, 2010

机译：KRaB锌指蛋白ZNF382是一种促凋亡肿瘤抑制因子，抑制多种致癌基因，通常在多种癌中沉默

Multiple changes in oncogenes and tumor suppressor genes in human retinoblastoma.

摘要

著录项

相似文献

相关主题

期刊订阅