Blood group genotyping for patients with autoimmune hemolytic anemia

摘要

We agree with the authors that the introduction of RBC antigen genotyping (including RH1; RH2, RH3, RH4, RH5, KEL1, FY1, FY2, JK1, JK2, MNS1, MNS2, MNS3, and MNS4) has provided considerable support to serology fos the assignment of blood components.6 Indeed, it has been reported that for patients with AIHA, as well as for those with sickle cell disease or thalassemia, pretransfusion conventional tests are considered difficult because of the presence of auto-and alloantibodies.7 The rate of alloimrnumzation in patients with AIHA is still greater than in those with sickle cell disease or thalassemia (both of which are supported regularly by our division).