Advanced mass spectrometric methods applied to the study of fate and removal of pharmaceuticals in wastewater treatment

摘要

This overview is of analytical methodologies based on gas chromatography-mass spectrometry and liquid chromatography-mass spectrometry, applied in environmental monitoring of pharmaceutical residues and their known degradation products. We also consider the ability of time-of-flight (TOF) and quadrupole-TOF instruments to provide sufficiently accurate-mass measurements and full-scan spectra for unequivocal confirmation of target compounds and investigation of their degradation products, which are either known or unknown.