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首页> 外文期刊>The West Indian medical journal. >Life's immunity as a normal distribution function: philosophies for the use of dibenzyl trisulphide in immunity enhancement and life extension.
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Life's immunity as a normal distribution function: philosophies for the use of dibenzyl trisulphide in immunity enhancement and life extension.

机译:生命的免疫力作为正态分布函数:关于三硫化二苄基用于增强免疫力和延长寿命的哲学。

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摘要

The thymus is an immunological endocrine organ located in the middle mediastinum. The organ is bi-lobed and large during the first few years of life and then shrinks considerably as the body ages (1). As the thymus shrinks (atrophy), it is infiltrated with fatty tissue and strands of fibrous connective tissue. The process by which the thymus undergoes atrophy is known as involution and sets in at about age 28 years old. Involution is marked by a decrease in size of the thymus, decreased cellularity, decline in the production of new cells from the bone marrow, decline in responsiveness to vaccines and increased incidence in autoimmune diseases (2; 3). It is the author's belief that dibenzyl trisulphide (DTS) is capable of reversing the process of involution of the thymus based on data obtained from studies conducted in old mice (4, 5). This suggests that DTS may be capable of delaying the onset of ageing (degenerative) diseases such as osteo-arthritis and some forms of cancer.
机译:胸腺是位于纵隔中部的免疫内分泌器官。器官在生命的最初几年中呈双瓣状且很大,然后随着年龄的增长而明显缩小(1)。当胸腺萎缩(萎缩)时,脂肪组织和纤维结缔组织束会渗入胸腺。胸腺萎缩的过程被称为内卷化,大约在28岁时开始。复性的特征是胸腺大小减少,细胞数量减少,骨髓新细胞产量下降,对疫苗的反应性下降以及自身免疫性疾病的发生率增加(2; 3)。作者相信,根据对老年小鼠进行的研究获得的数据,二苄基三硫化物(DTS)能够逆转胸腺的退化过程(4,5)。这表明DTS可能能够延缓衰老(变性)疾病(如骨关节炎和某些形式的癌症)的发作。

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