method for inhibiting immune evasion, method for treating immune dysfunction, method for enhancing an immune response, method for increasing expression of a major histocompatibility complex, method for increasing inflammation, method for treating cancer or cell proliferative disorder, method to determine the likelihood of efficacy of a treatment, and method for screening the efficacy of a treatment

摘要

it is a method for treating or alleviating a symptom of the disorder, for example, immune evasion, cancer cell-induced immune dysfunction, reduced immune response, decreased inflammation, decreased expression of a major histocompatibility complex (mhc), or cancer, distinguished by the aberrant, unregulated or increased zeste 2 homologue (ezh2) activity in a cell or individual in need thereof in contact with the cell or administering to the individual a therapeutically effective amount of an ezh2 inhibitor.