HLA-A 02:335 and HLA-A 02:370 were identified by polymerase chain reaction sequence-based typing in Chinese individuals

摘要

The human leukocyte antigen (HLA) system is well known as a highly polymorphism genetic system. The region plays an important role in the immune response and displays a marked degree of genetic polymorphism. Molecular analysis of the HLA region has enhanced the usefulness of this system for selecting donors for hematopoietic cell transplantation, for investigation of disease associations and for anthropo-logic population studies (1, 2). Now the use of molecular typing methods for defining HLA alleles is commonplace in hematopoietic stem cell donors and recipients,