Applying inappropriate cutoffs leads to misinterpretation of folate status in the US population

摘要

Background: Folate cutoffs for risk of deficiency compared with possible deficiency were originally derived differently (experimental compared with epidemiologic data), and their interpretations are different. The matching of cutoffs derived from one assay with population-based data derived from another assay requires caution. Objective: We assessed the extent of folate-status misinterpretation with the use of inappropriate cutoffs.