Tigecycline: benefits and risks.

摘要

"Antimicrobial resistance: no action today, no cure tomorrow", the theme for World Health Day 2011, shows the helplessness of the human predicament. Thus, any new antibiotics effective against strains resistant to existing drugs would gain worldwide attention. Tigecycline is one such antibiotic, with efficacy against many multidrug-resistant pathogens widely reported.In The Lancet Infectious Diseases, Efthimia Tasina and colleagues1 report their findings from a meta-analysis of tigecycline. This study updates Cai and colleagues' meta-analysis,2 published 7 months ago, with inclusion of new and unpublished reports. Undoubtedly, the inclusion of more randomised control trials in Tasina and colleagues' study makes the results of the safety assessment more convincing.