Acute Ischemic Stroke and Transient Ischemic Attack: An Update on Recent Practically Relevant Clinical Trials

摘要

This short review focuses on recent practically relevant studies in stroke treatment and prevention and discusses their implications on clinical practice and future research, including 3 shortly published randomized controlled trials investigating interventional treatment in acute ischemic stroke (The Inter-ventional Management of Stroke phase III trial [IMS III], Synthesis Expansion: A Randomized Controlled Trial on Intra-Arterial Versus Intravenous Thrombolysis in Acute Ischemic Stroke, and the Mechanical Retrieval and Recanali-zation of Stroke Clots Using Embolectomy [MR RESCUE]) and 1 large trial on secondary prevention in high-risk patients with transient ischemic attack (TIA) or minor stroke (Randomized, Double-blind Trial Comparing the Effects of a 3-month Clopidogrel Regimen, Combined With ASA During the First 21 days, Versus ASA Alone for the Acute Treatment of TIA or Minor Stroke [CHANCE trial]).