首页> 外文期刊>The Journal of Thoracic and Cardiovascular Surgery >Surgery for acute type A dissection using total arch replacement combined with stented elephant trunk implantation: experience with 107 patients.
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Surgery for acute type A dissection using total arch replacement combined with stented elephant trunk implantation: experience with 107 patients.

机译:使用全弓置换结合支架式大象躯干植入术进行急性A型解剖的经验:107例患者的经验。

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OBJECTIVE: In patients with acute type A dissection, it is controversial whether to use a more aggressive strategy with extended aortic replacement to improve long-term outcome or to use a conventional strategy with limited ascending aortic or hemiarch replacement to circumvent a life-threatening situation. METHODS: Between April 2003 and June 2007, 107 patients (17 women, 90 men; mean age, 45 +/- 11 years; range, 17-78 years) with acute type A dissection underwent total arch replacement combined with stented elephant trunk implantation under hypothermic cardiopulmonary bypass and selective cerebral perfusion. Computed tomography was performed to evaluate the residual false lumen in the descending aorta during follow-up. RESULTS: Thirty-day mortality was 3.74% (4/107 patients), and in-hospital mortality was 4.67% (5/107 patients). Spinal cord injury was observed in 3 patients (1 patient with left lower-extremity paraparesis and 2 patients with paraplegia). Cerebral infarction was observed in 3 patients, ventilator support exceeding 5 days was required in 9 patients, and rebleeding was observed in 4 patients. During a mean follow-up of 35 +/- 14 months, 3 patients died and 3 patients were lost to follow-up. On postoperative computed tomography, complete thrombus formation was observed around the stented elephant trunk in 95% of patients (95/100) and at the diaphragmatic level in 69% of patients (69/100). CONCLUSION: Low morbidity and mortality were achieved using total arch replacement combined with stented elephant trunk implantation. These encouraging surgical results and postoperative outcomes favor this more aggressive procedure for acute type A dissection.
机译:目的:对于急性A型夹层的患者,是否采用更具积极性的策略,扩大主动脉置换以改善长期预后,还是采用常规的有限升主动脉或半主动脉置换策略来危及生命的情况存在争议。 。方法:2003年4月至2007年6月,对107例急性A型剥离患者(17名女性,90名男性;平均年龄:45 +/- 11岁;年龄范围:17-78岁)进行了全弓置换并联合了支架植入象鼻。低温体外循环和选择性脑灌注。进行计算机断层扫描以评估随访期间降主动脉中的残留假管腔。结果:30天死亡率为3.74%(4/107例患者),住院死亡率为4.67%(5/107例患者)。 3名患者(1名左下肢轻瘫和2名截瘫)观察到脊髓损伤。 3例患者出现脑梗塞,9例患者需要超过5天的呼吸机支持,4例患者出现再出血。在平均35 +/- 14个月的随访期间,有3例患者死亡,有3例失去随访。在术后计算机体层摄影术中,在95%的患者(95/100)和在diaphragm肌水平的69%(69/100)的患者中,在带支架的大象躯干周围观察到完全的血栓形成。结论:采用全弓置换术联合带支架大象树干植入术可降低发病率和死亡率。这些令人鼓舞的手术结果和术后结果有利于急性A型夹层这种更具侵略性的手术。

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