首页> 外文期刊>The Journal of Thoracic and Cardiovascular Surgery >Influence of operative strategy for the aortic arch in DeBakey type I aortic dissection: Analysis of the German Registry for Acute Aortic Dissection Type A
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Influence of operative strategy for the aortic arch in DeBakey type I aortic dissection: Analysis of the German Registry for Acute Aortic Dissection Type A

机译:DeBakey I型主动脉夹层中主动脉弓手术策略的影响:德国A型急性主动脉夹层注册表的分析

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Objective: Patients treated with an extensive approach including total aortic arch replacement for acute aortic dissection type A may have a favorable long-term prognosis by treating the residual false lumen. Our goal was to analyze the operative strategy for treatment of type I DeBakey aortic dissection from the German Registry for Acute Aortic Dissection Type A (GERAADA) data. Methods: A total of 658 patients with type I DeBakey aortic dissection and entry only in the ascending aorta were identified in the GERAADA. Patients in group A underwent replacement of the ascending aorta with hemi-arch replacement. Patients in group B received extensive treatment with total arch replacement or conventional or frozen elephant trunk. Results: A total of 518 patients in group A and 140 patients in group B were treated. There was an overall 30-day mortality of 20.2% (n = 133). Group A had a slightly lower rate of mortality with 18.7% (n = 97) compared with 25.7% for group B (n = 36), but with no statistical significant difference (P = .067). The onset of new neurologic deficit (13.6% in group vs 12.5% in group B, P = .78) and new malperfusion deficit (8.4% in group A vs 10.7% in group B, P = .53) showed no statistical difference. Conclusions: On analysis of the GERAADA data, it seems that a more aggressive approach of aortic arch treatment can be applied without higher perioperative risk even in the onset of acute aortic dissection type A. Long-term follow-up data analysis will be necessary to offer the optimal surgical strategy for different patient groups.
机译:目的:采用包括全主动脉弓置换术在内的广泛方法治疗急性A型主动脉夹层的患者,通过治疗残留的假管腔可能具有良好的长期预后。我们的目标是根据德国A型急性主动脉夹层资料库(GERAADA)来分析治疗I型DeBakey主动脉夹层的手术策略。方法:在GERAADA中鉴定了658例I型DeBakey主动脉夹层且仅在升主动脉内进入的患者。 A组患者接受升主动脉置换半弓置换术。 B组患者接受了全面的弓置换术或常规或冷冻象鼻的广泛治疗。结果:A组共518例,B组140例。 30天总死亡率为20.2%(n = 133)。 A组的死亡率稍低,为18.7%(n = 97),而B组的死亡率为25.7%(n = 36),但无统计学显着性差异(P = .067)。新发神经功能缺损(B组为13.6%,B组为12.5%,P = .78)和新的灌流不足(A组为8.4%,B组为10.7%,P = .53)的发生无统计学差异。结论:在分析GERAADA数据时,似乎即使在A型主动脉夹层急性发作时,也可以采用更具侵略性的主动脉弓治疗方法,而没有较高的围手术期风险。长期随访数据分析对于为不同的患者群体提供最佳的手术策略。

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