Gold(I)-catalyzed tandem transformation: A simple approach for the synthesis of pyrrolo/pyrido[2,1- a ][1,3]benzoxazinones and pyrrolo/pyrido[2,1- a ]quinazolinones

摘要

We have developed a simple method for the synthesis of pyrrolo/pyrido[2,1- a][1,3]benzoxazinones and pyrrolo/pyrido[2,1-a]quinazolinones from 2-amino benzoic acids and 2-amino benzamides via a gold(I)-catalyzed tandem coupling/cyclization process. The tricyclic or polycyclic molecular architectures were constructed in one pot with the formation of three new bonds.