Oxygen saturation as a predictor of prolonged, frequent bronchodilator therapy in children with acute asthma.

摘要

Objectives To examine if the initial oxygen saturation (Sa o 2 ) in the Emergency Department is a useful predictor of prolonged frequent bronchodilator therapy (FBT) in children with acute asthma. Study design Prospective cohort study of 273 children, 1 to 17 years of age, requiring systemic corticosteroids. Patients were categorized as needing FBT for >4 hours (n = 166) versus >4 hours (n = 107) and >12 hours (n = 79) versus >12 hours (n = 194). Multiple logistic regression determined the association between Sa o 2 and these outcomes. Results Baseline Sa o 2 remains a significant independent predictor of FBT for >4 hours (OR = 0.81) and >12 hours (OR = 0.84); 91% of patients with Sa o 2 of 90% to 91% had FBT >4 hours and 80% of patients with Sa o 2 of 12 hours. Children with Sa o 2 of 4 hours and >12 hours, respectively, than those with Sa o 2 of 98% to 100%. The interval likelihood ratios for FBT >4 hours were 12.3 for Sa o 2 of 12 hours decreased from 9.8 for Sa o 2 of 4 hours if it is 12 hours if it is