QUINAZOLINE ALKALOIDS FROM Streptomyces michiganensis

摘要

Two new quinazoline alkaloids, 2-(2-carboxyethyl)-8-hydroxyquinazolin-4(3H)-one (1) and 2-(2-carboxyethyl)- 6-hydroxyquinazolin-4(3H)-one (2), along with the previously synthesized 2-(4-hydroxyphenyl)quinazolin- 4(3H)-one (3), were isolated from the solid cultures of Streptomyces michiganensis strain SC0642. Their structures were elucidated by spectroscopic methods.