首页> 外文期刊>The Journal of Immunology: Official Journal of the American Association of Immunologists >IL-18-Binding Protein Protects Against Lipopolysaccharide-Induced Lethality and Prevents thhe Development of Fas/Fas Ligand-Mediated Models of Liver Disease in Mice
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IL-18-Binding Protein Protects Against Lipopolysaccharide-Induced Lethality and Prevents thhe Development of Fas/Fas Ligand-Mediated Models of Liver Disease in Mice

机译:IL-18结合蛋白可防止脂多糖诱导的致死性并阻止Fas / Fas配体介导的小鼠肝脏疾病模型的发展

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摘要

IL-18-binding protein (IL-18BP) is a natural IL-18 inhibitor. Human IL-18BP isoform a was produced as fusion construct with human IgG1 Fc and assessed for binding and neutralizing IL-18.
机译:IL-18结合蛋白(IL-18BP)是天然的IL-18抑制剂。产生人IL-18BP同工型a作为与人IgG1 Fc的融合构建体,并评估其结合和中和IL-18。

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