Moxifloxacin is not anti-inflammatory in experimental pneumococcal pneumonia

Mueller-Redetzky H. C.; Wienhold S. M.; Berg J.; Hocke A. C.; Hippenstiel S.; Hellwig K.; Gutbier B.; Opitz B.; Neudecker J.; Rueckert J.; Gruber A. D.; Kershaw O.; Mayer K.; Suttorp N.; Witzenrath M.

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Moxifloxacin is not anti-inflammatory in experimental pneumococcal pneumonia

机译：莫西沙星在实验性肺炎球菌性肺炎中不消炎

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Objectives: Anti-inflammatory functions of antibiotics may counteract deleterious hyperinflammation in pneumonia. Moxifloxacin reportedly exhibits immunomodulatory properties, but experimental evidence in pneumonia is lacking. Therefore, we investigated moxifloxacin in comparison with ampicillin regarding pneumonia-associated pulmonary and systemic inflammation and lung injury.

机译：目的：抗生素的抗炎功能可以抵消肺炎中有害的过度炎症。据报道莫西沙星具有免疫调节特性，但缺乏肺炎的实验证据。因此，我们调查了莫西沙星与氨苄西林在肺炎相关的肺和全身炎症以及肺损伤方面的比较。

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《The Journal of Antimicrobial Chemotherapy》 |2015年第3期|共11页
作者
Mueller-Redetzky H. C.; Wienhold S. M.; Berg J.; Hocke A. C.; Hippenstiel S.; Hellwig K.; Gutbier B.; Opitz B.; Neudecker J.; Rueckert J.; Gruber A. D.; Kershaw O.; Mayer K.; Suttorp N.; Witzenrath M.;
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正文语种 eng
中图分类治疗学;
关键词
inflammation; Streptococcus pneumoniae; acute lung injury; antibiotics;

机译：炎症;肺炎链球菌;急性肺损伤;抗生素;

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1. Moxifloxacin is not anti-inflammatory in experimental pneumococcal pneumonia [J] . Mueller-Redetzky H. C., Wienhold S. M., Berg J., The Journal of Antimicrobial Chemotherapy . 2015,第3期

机译：莫西沙星在实验性肺炎球菌性肺炎中不消炎
2. In vitro interactions of LytA, the major pneumococcal autolysin, with two bacteriophage lytic enzymes (Cpl-1 and Pal), cefotaxime and moxifloxacin against antibiotic-susceptible and -resistant Streptococcus pneumoniae strains [J] . Violeta Rodríguez-Cerrato1 Pedro García2 Gema del Prado1 Ernesto García2 Matilde Gracia1 Lorena Huelves1 Carmen Ponte1 Rubens López2 and Francisco Soriano1 Journal of Antimicrobial Chemotherapy . 2007,第5期

机译：LytA（主要的肺炎球菌自溶素）与两种噬菌体裂解酶（Cpl-1和Pal），头孢噻肟和莫西沙星在体外对抗生素敏感和耐药的肺炎链球菌菌株的相互作用
3. In vitro interactions of LytA, the major pneumococcal autolysin, with two bacteriophage lytic enzymes (Cpl-1 and Pal), cefotaxime and moxifloxacin against antibiotic-susceptible and -resistant Streptococcus pneumoniae strains. [J] . Rodriguez-Cerrato V, Garcia P, Del-Prado G, The Journal of Antimicrobial Chemotherapy . 2007,第5期

机译：LytA（主要的肺炎球菌自溶素）与两种噬菌体裂解酶（Cpl-1和Pal），头孢噻肟和莫西沙星在体外对抗生素敏感和耐药的肺炎链球菌菌株的相互作用。
4. EVALUATION OF A NEW MYCOPLASMA HYOPNEUMONIAE (M.hyo) BACTERIN TO CONTROL MYCOPLASMA PNEUMONIA IN PIGS EXPERIMENTALLY COINFECTED WITH PRRSV AND MYCOPLASMA HYPNEUMONIAE [C] . E .Thacker, D. Nilubol, R. Evans Congress ofthe International Pig Veterinary Society . 2008

机译：评估新的支原体纵向藓（M.Hyo）细菌在用PRRSV和支原体缺血试验繁殖的猪中测定猪的支原体肺炎
5. The molecular analysis of quinolone-resistant and nonencapsulated Streptococcus pneumoniae after the introduction of new oral fluoroquinolone and pneumococcal conjugate vaccine [D] . TAKEUCHI, Noriko 2019

机译：新型口服氟喹诺酮和肺炎球菌结合疫苗接种后对喹诺酮耐药和非包膜肺炎链球菌的分子分析
6. Mutant Selection Window in Levofloxacin and Moxifloxacin Treatments of Experimental Pneumococcal Pneumonia in a Rabbit Model of Human Therapy [O] . Delphine Croisier, Manuel Etienne, Emilie Bergoin, 2004

机译：左氧氟沙星和莫西沙星治疗实验性肺炎球菌性肺炎的人治疗模型兔中的突变选择窗口
7. Moxifloxacin is not anti-inflammatory in experimental pneumococcal pneumonia [O] . H. C. Müller-Redetzky, S. M. Wienhold, J. Berg, 2014

机译：Moxifloxacin在实验性肺炎骨球菌肺炎中不是抗炎

Moxifloxacin is not anti-inflammatory in experimental pneumococcal pneumonia

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