Immunologic response and safety in birch pollen sublingual versus oral vestibule immunotherapy: A pilot study

摘要

To date the efficacy of sublingual immunotherapy (SLIT) in the form of allergy immunotherapy tablets is well documented with a large number of clinical trials and it is accepted as an effective alternative to subcutaneous immunotherapy in the treatment of type I-mediated respiratory allergies in Europe, but is currently not likewise accepted in the United States. The attention of many scientists and clinicians is directed toward how immunologic mechanisms mediate the effect of SLIT and improvement of its efficacy, while reducing adverse effects.