Safety profile and immunological response of dual sublingual immunotherapy with house dust mite tablet and Japanese cedar pollen tablet

Gotoh Minoru; Okubo Kimihiro; Yuta Atsushi; Ogawa Yukiko; Nagakura Hitoshi; Ueyama Shigehiro; Ueyama Tomoyo; Kawashima Kayoko; Yamamoto Masashi; Fujieda Shigeharu; Sakashita Masafumi; Sakamoto Hirokazu; Iwasaki Naruhito; Mori Eri; Endo Tomonori; Ohta Nobuo; Kitazawa Hiroshi; Okano Mitsuhiro; Asako Mikiya; Takada Masami; Terada Tetsuya; Inaka Yuko; Yonekura Syuji; Matsuoka Tomokazu; Kaneko Shinya; Hata Hiroki; Hijikata Nagisa; Tanaka Hisataka; Masuyama Keisuke; Okamoto Yoshitaka

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Safety profile and immunological response of dual sublingual immunotherapy with house dust mite tablet and Japanese cedar pollen tablet

机译：双舌下免疫疗法与日本雪松花粉片的安全剖面与免疫响应

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Background: There have been no studies of dual administration of sublingual immunotherapy (SLIT) tablets for perennial and seasonal allergic rhinitis. This trial (JapicCTI-184014) was conducted to investigate the safety profile and immunological response during dual therapy with SQ house dust mite (HDM) and Japanese cedar pollen (JCP) SLIT tablets.

机译：背景：对常年和季节性过敏性鼻炎的舌下免疫疗法（狭缝）片进行双重管理。进行该试验（Japiccti-184014）以研究双重治疗的安全性曲线和免疫应答，SQ House粉尘（HDM）和日本雪松花粉（JCP）狭缝片。

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来源
《Allergology international: official journal of the Japanese Society of Allergology》 |2020年第1期|共7页
作者
Gotoh Minoru; Okubo Kimihiro; Yuta Atsushi; Ogawa Yukiko; Nagakura Hitoshi; Ueyama Shigehiro; Ueyama Tomoyo; Kawashima Kayoko; Yamamoto Masashi; Fujieda Shigeharu; Sakashita Masafumi; Sakamoto Hirokazu; Iwasaki Naruhito; Mori Eri; Endo Tomonori; Ohta Nobuo; Kitazawa Hiroshi; Okano Mitsuhiro; Asako Mikiya; Takada Masami; Terada Tetsuya; Inaka Yuko; Yonekura Syuji; Matsuoka Tomokazu; Kaneko Shinya; Hata Hiroki; Hijikata Nagisa; Tanaka Hisataka; Masuyama Keisuke; Okamoto Yoshitaka;
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作者单位

Nippon Med Sch Grad Sch Med Dept Otolaryngol Head &

Neck Surg Tokyo Japan;

Nippon Med Sch Grad Sch Med Dept Otolaryngol Head &

Neck Surg Tokyo Japan;

Yuta Clin Tsu Mie Japan;

Yuta Clin Tsu Mie Japan;

Nagakura Ear Nose &

Throat Allergy Clin Tokyo Japan;

Funai ENT Clin Oita Japan;

Funai ENT Clin Oita Japan;

Osaka Prefectural Hosp Org Osaka Habikino Med Ctr Osaka Japan;

Osaka Prefectural Hosp Org Osaka Habikino Med Ctr Osaka Japan;

Univ Fukui Fac Med Sci Dept Sensory &

Locomotor Med Div Otorhinolaryngol Head &

Neck Surg Fukui;

Univ Fukui Fac Med Sci Dept Sensory &

Locomotor Med Div Otorhinolaryngol Head &

Neck Surg Fukui;

Osaka City Univ Grad Sch Med Dept Otolaryngol Head &

Neck Surg Osaka Japan;

Osaka City Univ Grad Sch Med Dept Otolaryngol Head &

Neck Surg Osaka Japan;

Jikei Univ Dept Otorhinolaryngol Sch Med Tokyo Japan;

Jikei Univ Dept Otorhinolaryngol Sch Med Tokyo Japan;

Tohoku Med &

Pharmaceut Univ Hosp Div Otolaryngol Sendai Miyagi Japan;

Tohoku Med &

Pharmaceut Univ Hosp Div Pediat Sendai Miyagi Japan;

Int Univ Hlth &

Welf Sch Med Dept Otorhinolaryngol Otawara Tochigi Japan;

Kansai Med Univ Div Otolaryngol Head &

Neck Surg Med Ctr Osaka Japan;

Kansai Med Univ Div Otolaryngol Head &

Neck Surg Med Ctr Osaka Japan;

Osaka Med Coll Dept Otolaryngol Osaka Japan;

Osaka Med Coll Dept Otolaryngol Osaka Japan;

Chiba Univ Grad Sch Med Dept Otolaryngol Head &

Neck Surg Chiba Japan;

Yamanashi Univ Grad Sch Med Dept Otorhinolaryngol Head &

Neck Surg Kofu Yamanashi Japan;

Torii Pharmaceut Co Ltd Tokyo Japan;

Torii Pharmaceut Co Ltd Tokyo Japan;

Torii Pharmaceut Co Ltd Tokyo Japan;

Torii Pharmaceut Co Ltd Tokyo Japan;

Yamanashi Univ Grad Sch Med Dept Otorhinolaryngol Head &

Neck Surg Kofu Yamanashi Japan;

Chiba Univ Grad Sch Med Dept Otolaryngol Head &

Neck Surg Chiba Japan;

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原文格式 PDF
正文语种 eng
中图分类免疫性疾病;
关键词
Allergic rhinitis; Dual therapy; Immunological response; Safety; Sublingual immunotherapy;

机译：过敏性鼻炎;双重治疗;免疫应答;安全;舌下免疫疗法;
入库时间 2022-08-20 00:51:55

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专利

1. Safety profile and immunological response of dual sublingual immunotherapy with house dust mite tablet and Japanese cedar pollen tablet [J] . Minoru Gotoh, Kimihiro Okubo, Atsushi Yuta, Allergology international: official journal of the Japanese Society of Allergology . 2020,第1期

机译：室内尘螨片和日本雪松花粉片双重舌下免疫疗法的安全性和免疫应答
2. Dual sublingual immunotherapy with Japanese Cedar Pollen droplets and House Dust Mite tablets [J] . Tomokazu Matsuoka, Satoshi Igarashi, Yuumi Kuroda, Allergology international: official journal of the Japanese Society of Allergology . 2019,第4期

机译：日本雪松花粉小滴和House Dust Mite片双重舌下免疫疗法
3. Dual sublingual immunotherapy with Japanese Cedar Pollen droplets and House Dust Mite tablets [J] . Matsuoka Tomokazu, Igarashi Satoshi, Kuroda Yuumi, Allergology international: official journal of the Japanese Society of Allergology . 2019,第4期

机译：双舌下免疫疗法与日本雪松花粉液滴和房屋尘螨片剂
4. Sublingual immunotherapy in children with house dust mite induced allergic asthma [C] . Kumar Suman, Pey N., Sharma Nirankar, International Primary Care Respiratory Group . 2010

机译：含有房屋粉尘诱发过敏性哮喘的儿童的舌下免疫疗法
5. Structural, Functional and Immunological Studies of Group 1 and 2 House Dust Mite and Profilin Allergens for the Development of Allergen Specific Diagnostics and Immunotherapy [D] . Kapingidza, Anyway B. 2020

机译：第1族和2次房屋粉尘和毛细血管过敏原特异性诊断和免疫疗法的结构，功能和免疫学研究
6. Sublingual Immunotherapy 1: 157 The Post-Treatment Efficacy of House Dust Mite Sublingual Allergen Immunotherapy Tablets in Adults With Allergic Rhinitis [O] . Karl-Christian Bergmann, Pascal Demoly, Margitta Worm, 2012

机译：舌下免疫治疗1：157成人尘螨过敏性鼻炎的房尘螨舌下变应原免疫治疗片的治疗后功效
7. Safety of Dual Sublingual Immunotherapy with Japanese Cedar Pollen and SQ House Dust Mite Tablets in Children, Adolescents and Adults [O] . Yoshitaka Okamoto, Syuji Yonekura, Minoru Gotoh, 2020

机译：儿童，青少年和成人的双糖尿病与日本雪松花粉和SQ House尘螨片的安全性

Safety profile and immunological response of dual sublingual immunotherapy with house dust mite tablet and Japanese cedar pollen tablet

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