IgE antibodies, Fc epsilon RI alpha, and IgE-mediated local anaphylaxis can limit snake venom toxicity

摘要

Background: Type 2 cytokine-related immune responses associated with development of antigen-specific IgE antibodies can contribute to pathology in patients with allergic diseases and to fatal anaphylaxis. However, recent findings in mice indicate that IgE also can enhance defense against honeybee venom.