Pharmacotherapy for borderline personality disorder: NICE guideline.

摘要

In their review of drug treatments for borderline personality disorder, Lieb et al, despite considering similar evidence, draw largely different conclusions from those we drew when developing the National Institute for Health and Clinical Excellence (NICE) guideline. Lieb et al recommend a range of drugs. These include anticonvulsants for affective dysregulation symptoms (topiramate, valproate semisodium and lamotrigine) and impulsive-behavioural dyscontrol symptoms (lamotrigine and topiramate); and anti-psycho tics (aripiprazole and olanzapine) for cognitive-perceptual symptoms. In contrast, we do not recommend drug treatment other than for the treatment of comorbid disorders.