Enzymatic synthesis of 3-deoxy-D-manno-2-octulosonic acid and analogues: A new approach by a non metabolic pathway

摘要

A new approach to acceed to 4-deoxy-KDO is described. The key step is the formation of the C-5-C-6 bond catalyzed by fructose-1,6-bisphosphate aldolase which controls the stereochemistry of these two centers. (C) 1999 Published by Elsevier Science Ltd. All rights reserved. [References: 16]