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Effects of Concomitant Surgeries During Midurethral Slings (MUS) on Postoperative Complications, Voiding Dysfunction, Continence Outcomes, and Urodynamic Variables

机译:尿道中段吊带术(MUS)伴随手术对术后并发症,排尿功能障碍,排尿结局和尿动力学变量的影响

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OBJECTIVE:To determine whether concomitant surgeries affected outcomes in a randomized trial comparing retropubic midurethral sling (MUS) vs transobturator MUS. METHODS:Subjects (n = 597) were stratified into 4 groups based on type of concomitant surgeries: group I had anterior/apical with or without posterior repairs (n = 79, 13%); group II had posterior repairs or perineorrhaphy only (n = 38, 6%); group III had nonprolapse procedures (n = 34, 6%); and group IV had no concomitant surgeries (n = 446, 75%). Complication rates, voiding dysfunction, objective and subjective surgical failure rates, and changes in urodynamic values (postop minus preop) were assessed and compared in these 4 groups.RESULTS:There were no differences in complications, voiding dysfunction, and subjective failure outcomes between these 4 groups. Group I had lower odds ratio of objective surgical failure compared with group IV (OR 0.38, 95% CI 0.18-0.81, P = .05). The OR of failure of all patients undergoing concomitant surgeries (groups I-III) was lower than group IV (OR 0.57, 95% CI 0.35-0.95, P = .03). The change in Pdet@Qmax (from pressure-flow) was significantly higher in group III vs IV (P = .01). The change in Q_(max). (from uroflowmetry) was significantly less in groups I and II vs group IV (P = .046 and .04, respectively).CONCLUSION:Concomitant surgeries did not increase complications. Subjects who underwent certain concomitant surgeries had lower failure rates than those undergoing slings only. These data support safety and efficacy of performing concomitant surgery at the time of MUS.
机译:目的:通过比较耻骨后中段尿道吊带(MUS)与经闭孔MUS进行的一项随机试验,确定伴随手术是否影响预后。方法:根据伴随手术的类型,将受试者(n = 597)分为4组:第一组为前/心尖,有或没有后路修复(n = 79,13%);第一组为前/顶或后修复。第二组仅进行后路修复或围手术期(n = 38,6%);第三组没有脱垂手术(n = 34,6%); IV组无伴随手术(n = 446,75%)。评估并比较了这4组患者的并发症发生率,排尿功能障碍,客观和主观手术失败率以及尿动力学值的变化(术后减去前置手术)。 4组。与IV组相比,I组的客观手术失败几率较低(OR 0.38,95%CI 0.18-0.81,P = 0.05)。所有同时进行手术的患者(I-III组)的失败OR均低于IV组(OR 0.57,95%CI 0.35-0.95,P = .03)。与IV组相比,III组的Pdet @ Qmax(来自压力流)的变化明显更高(P = 0.01)。 Q_(max)的变化。 I组和II组(通过尿流法)明显少于IV组(分别为P = .046和.04)。结论:伴随手术并没有增加并发症。接受某些伴随手术的受试者的失败率低于仅接受吊带术的受试者。这些数据支持在进行MUS时进行伴随手术的安全性和有效性。

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