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Novel styryldehydropyridocolinium derivative as turn-on fluorescent probe for DNA detection

机译:新型苯乙烯基脱氢吡啶并吡啶鎓衍生物作为用于DNA检测的开启荧光探针

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摘要

Novel styryldehydropyridocolinium derivative L was prepared and found to have low fluorescence quantum yield in water; however, upon addition of DNA, the fluorescence intensity increased by a factor of 60-fold. Meanwhile, it also showed rapid cellular uptake properties in cell imaging due to its cationic structure favored for cell membrane permeability.
机译:制备了新型的苯乙烯基脱氢吡啶并吡啶鎓衍生物L,发现其在水中的荧光量子产率较低;但是,添加DNA后,荧光强度增加了60倍。同时,由于其阳离子结构有利于细胞膜通透性,它在细胞成像中也显示出快速的细胞摄取特性。

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  • 来源
    《Sensors and Actuators》 |2014年第10期|483-488|共6页
  • 作者单位

    Key Laboratory of Display Materials & Photoelectric Devices, Ministry of Education, School of Materials Science & Engineering, Tianjin University of Technology, Tianjin 300384, China;

    Key Laboratory of Display Materials & Photoelectric Devices, Ministry of Education, School of Materials Science & Engineering, Tianjin University of Technology, Tianjin 300384, China;

    Key Laboratory of Display Materials & Photoelectric Devices, Ministry of Education, School of Materials Science & Engineering, Tianjin University of Technology, Tianjin 300384, China;

    Key Laboratory of Display Materials & Photoelectric Devices, Ministry of Education, School of Materials Science & Engineering, Tianjin University of Technology, Tianjin 300384, China;

    Key Laboratory of Display Materials & Photoelectric Devices, Ministry of Education, School of Materials Science & Engineering, Tianjin University of Technology, Tianjin 300384, China;

    Key Laboratory of Display Materials & Photoelectric Devices, Ministry of Education, School of Materials Science & Engineering, Tianjin University of Technology, Tianjin 300384, China ,School of Materials Science and Engineering, Harbin Institute of Technology, Harbin 150001, China;

    Key Laboratory of Display Materials & Photoelectric Devices, Ministry of Education, School of Materials Science & Engineering, Tianjin University of Technology, Tianjin 300384, China;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    Fluorescence spectroscopy; Sensor; Dye; DNA; Cell staining;

    机译:荧光光谱法;传感器;染料;脱氧核糖核酸;细胞染色;

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