Combinatorial Chemistry Hits the Drug Market

摘要

Combinatorial chemistry is a hot field, and if interest from company job scouts is any gauge, it's only getting hotter. It burst on the scene in the early 1990s as a way to simultaneously create and then test thousands of related compounds for variouskinds of activity, potentially fast-forwarding the process of drug discovery. And now "people on our project are getting calls from headhunters every day," says Steven Goldstein, who runs the combinatorial chemistry program at Pfizer in Groton, Connecticut.