Preliminarily functional analysis of a cloned novel human gene ADAM29

摘要

ADAM is a family of type l integral membrane proteins which are characterized by shar- ing a disintegrin and metalloprotease domain and involved in many important physiological proc- esses such as fertilization, neurogenesis and inflammatory response. A novel human ADAM gene -ADAM29, which was cloned in our laboratory, is exclusivley expressed in human testis and contains a potential fusion domain. A full-length cDNA to ADAM29 was obtained by using multi- ple-step PCR.