Clone analysis of functional genomics analysis, and compositions for performing the clones analyzed

摘要

A method of clonal analysis of the functional genome analysis is provided. Aspect of the invention, a population of target cells in virus effector library packaged are composed of a plurality of effector constructs subset includes that transduce, the effector construct a subset of the viral effector libraries respectively different It includes a plurality of effectors constructs having a common effector cassette attached to clone the bar code. By including Crohn barcode different effector constructs subsets, it is possible to determine the clones displaying effector construct a subset of the target cells transduced show a specific phenotype. Aspect of the invention, the composition used in the execution of the method, further comprises the elements of such a library and library.