In vivo electrophysiological and neurochemical effects of the selective 5-HT1A</sub> receptor agonist, F13640, at pre- and postsynaptic 5-HT1A</sub> receptors in the rat

Laia Lladó-Pelfort; Marie-Bernadette Assié; Adrian Newman-Tancredi; Francesc Artigas; Pau Celada

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In vivo electrophysiological and neurochemical effects of the selective 5-HT1A receptor agonist, F13640, at pre- and postsynaptic 5-HT1A receptors in the rat

机译：选择性5-HT1A 受体激动剂F13640对大鼠突触前后5-HT1A 受体的体内电生理和神经化学作用

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F13640 (befiradol) is a novel 5-HT1A receptor agonist with exceptional selectivity vs. other receptors and binding sites. It shows analgesic activity in animal models and is currently developed for human use.

机译：F13640（befiradol）是一种新型的5-HT1A 受体激动剂，与其他受体和结合位点相比具有出色的选择性。它在动物模型中显示出止痛活性，目前已开发用于人类。

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来源
《Psychopharmacology》 |2012年第2期|p.261-272|共12页
作者
Laia Lladó-Pelfort; Marie-Bernadette Assié; Adrian Newman-Tancredi; Francesc Artigas; Pau Celada;
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作者单位

Department of Neurochemistry and Neuropharmacology, Institut d’Investigacions Biomèdiques de Barcelona, CSIC-IDIBAPS, Rosselló 161, 6th floor, 08036, Barcelona, Spain;

Neurobiology Division 2, Centre de Recherches Pierre Fabre, Castres, France;

Neurobiology Division 2, Centre de Recherches Pierre Fabre, Castres, France;

Department of Neurochemistry and Neuropharmacology, Institut d’Investigacions Biomèdiques de Barcelona, CSIC-IDIBAPS, Rosselló 161, 6th floor, 08036, Barcelona, Spain;

Department of Neurochemistry and Neuropharmacology, Institut d’Investigacions Biomèdiques de Barcelona, CSIC-IDIBAPS, Rosselló 161, 6th floor, 08036, Barcelona, Spain;

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正文语种 eng
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关键词
5-HT1A receptors; Dopamine; Prefrontal cortex; Pyramidal neurons; Serotonin neurons;

机译：5-HT1A受体;多巴胺;前额叶皮层;锥体神经元;血清素神经元;

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1. In vivo electrophysiological and neurochemical effects of the selective 5-HT1A receptor agonist, F13640, at pre- and postsynaptic 5-HT1A receptors in the rat. [J] . Laia Lladó-Pelfort, Marie-Bernadette Assié, Adrian Newman-Tancredi, Psychopharmacology . 2012,第2期

机译：选择性5-HT1A受体激动剂F13640对大鼠突触前和突触后5-HT1A受体的体内电生理和神经化学作用。
2. Effect of Pindolol on the Function of Pre- and Postsynaptic 5-HT1A Receptors: In Vivo Microdialysis and Electrophysiological Studies in the Rat Brain [J] . L Romero, N Bel, F Artigas, Neuropsychopharmacology . 1996,第4期

机译：品多洛尔对突触前和突触后5-HT1A受体功能的影响：大鼠脑中的体内微透析和电生理研究。
3. SSR181507, A Dopamine D2 Receptor Antagonist and 5-HT1A Receptor Agonist. I: Neurochemical and Electrophysiological Profile [J] . Neuropsychopharmacology . 2003,第12期

机译：SSR181507，一种多巴胺D2受体拮抗剂和5-HT1A受体激动剂。一：神经化学和电生理特征
4. Research on the Effects of 5-HT1A Receptor in Hippocampal CA1 Region in the Cognition of PTSD Rats [C] . Ling Lin, Guoliang Liu, Yinpo Zhang International Conference on Materials Engineering and Information Technology Applications . 2017

机译：5-HT1A受体在PTSD大鼠认知中5-HT1A受体在海马CA1区域的影响
5. Towards a quantitative representation of the cell signaling mechanisms of hallucinogens: Measurement and mathematical modeling of 5-HT1A and 5-HT2A receptor-mediated ERK1/2 activation. [D] . Chang, Chiung-wen (Violet). 2009

机译：致幻剂的细胞信号传导机制的定量表征：5-HT1A和5-HT2A受体介导的ERK1 / 2激活的测量和数学建模。
6. Preferential in vivo action of F15599 a novel 5-HT1A receptor agonist at postsynaptic 5-HT1A receptors [O] . L Lladó-Pelfort, M-B Assié, A Newman-Tancredi, 2010

机译：新型5-HT1A受体激动剂F15599对突触后5-HT1A受体的优先体内作用
7. In vivo electrophysiological and neurochemical effects of the selective 5-HT 1A receptor agonist, F13640, at pre- and postsynaptic 5-HT 1A receptors in the rat [O] . Lladó-Pelfort Laia, Artigas Francesc, Celada Pau 2013

机译：选择性5-HT 1A受体激动剂F13640对大鼠突触前和突触后5-HT 1A受体的体内电生理和神经化学作用

In vivo electrophysiological and neurochemical effects of the selective 5-HT1A receptor agonist, F13640, at pre- and postsynaptic 5-HT1A receptors in the rat

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