Inositol trisphosphate 3-kinase B (lnsP3KB) as a physiological modulator of myelopoiesis

Yonghui Jia; Fabien Loison; Hidenori Hattori; Yitang Li; Christophe Erneux; Shin-Young Park; Chong Gao; Li Chai; Leslie E. Silberstein; Stephane Schurmans; Hongbo R. Luo

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Inositol trisphosphate 3-kinase B (lnsP3KB) as a physiological modulator of myelopoiesis

机译：肌醇三磷酸3-激酶B（InsP3KB）作为骨髓生成的生理调节剂

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Inositol trisphosphate 3-kinase B (lnsP3KB) belongs to a family of kinases that convert inositol 1,4,5-trisphosphate (Ins(1,4,5)P3 or IP3) to inositol 1,3,4,5-tetrakisphosphate (Ins(1,3,4,5)P4). Previous studies have shown that disruption of lnsP3KB leads

机译：肌醇三磷酸3-激酶B（lnsP3KB）属于将肌醇1,4,5-三磷酸（Ins（1,4,5）P3或IP3）转化为肌醇1,3,4,5-四磷酸（P Ins（1,3,4,5）P4）。先前的研究表明，破坏lnsP3KB会导致

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来源
《Proceedings of the National Academy of Sciences of the United States of America》 |2008年第12期|4739-4744|共6页
作者
Yonghui Jia; Fabien Loison; Hidenori Hattori; Yitang Li; Christophe Erneux; Shin-Young Park; Chong Gao; Li Chai; Leslie E. Silberstein; Stephane Schurmans; Hongbo R. Luo;
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收录信息美国《科学引文索引》(SCI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
原文格式 PDF
正文语种 eng
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关键词
hematopoiesis; inositol phosphate; neutrophils;

机译：造血功能磷酸肌醇;中性粒细胞;

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专利

1. Structural identification of the myo-inositol 1,4,5-trisphosphate-binding domain in rat brain inositol 1,4,5-trisphosphate 3-kinase [J] . Christophe ERNEUX, Kazunaga TAKAZAWA, Shinji TOGASHI, The biochemical journal . 1997,第1期

机译：大鼠脑肌醇1,4,5-三磷酸3-激酶中肌醇1,4,5-三磷酸结合结构域的结构鉴定
2. Identification in extracts from AR4-2J cells of inositol 1,4,5-trisphosphate by its susceptibility to inositol 1,4,5-trisphosphate 3-kinase and 5-phosphatase [J] . F S Menniti, J W Putney, K Nogimori The biochemical journal . 1990,第1期

机译：通过对肌醇1,4,5-三磷酸3-激酶和5-磷酸酶的敏感性鉴定AR4-2J细胞的肌醇1,4,5-三磷酸酯的提取物
3. Regiospecific phosphohydrolases from Dictyostelium as tools for the chemoenzymatic synthesis of the enantiomers D-myo-inositol 1,2,4-trisphosphate and D-myo-inositol 2,3,6-trisphosphate: non-physiological, potential analogues of biologically active D [J] . Adelt S, Plettenburg O, Dallmann G, Bioorganic and Medicinal Chemistry Letters . 2001,第20期

机译：Dictyostelium的区域特异性磷酸水解酶作为化学酶法合成对映异构体D-肌醇1,2,4-三磷酸和D-肌醇2,3,6-三磷酸的工具：具有生物活性的D的非生理性，潜在类似物
4. Inositol trisphosphate and calcium oscillations [C] . Michael J. Berridge Biochemical Society Symposium . 2007

机译：肌醇三磷酸和钙振荡
5. Inositol (1,4,5) trisphosphate 3-kinase B (ItpkB) is central to thymic development by regulating Phosphoinositide 3-kinase (PI3K) downstream of mild and strong TCR signals. [D] . Sternberg, Luise. 2013

机译：肌醇（1,4,5）三磷酸3激酶B（ItpkB）通过调节轻度和强TCR信号下游的磷酸肌醇3激酶（PI3K）对胸腺发育至关重要。
6. Inositol trisphosphate 3-kinase B (InsP3KB) as a physiological modulator of myelopoiesis [O] . Yonghui Jia, Fabien Loison, Hidenori Hattori, 2008

机译：肌醇三磷酸3-激酶B（InsP3KB）作为骨髓生成的生理调节剂
7. Inositol trisphosphate 3-kinase B (InsP3KB) as a physiological modulator of myelopoiesis [O] . Jia, Yonghui, Loison, Fabien, Hattori, Hidenori, 2008

机译：肌醇三磷酸3-激酶B（InsP3KB）作为骨髓生成的生理调节剂

Inositol trisphosphate 3-kinase B (lnsP3KB) as a physiological modulator of myelopoiesis

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