A truncated mutant (residues 58-140) of the hepatitis B virus X protein retains transactivation function

摘要

The hepatitis B virus X protein (HBx) se- quence (154 aa) has been divided into six regions (A-F) based on its sequence homology with X proteins of other mammalian hepadnaviruses. Regions A, C, and E are more conserved and include all the four conserved cysteines (C~7, C~61, C~69, and C~137).