Human stanniocalcin: A possible hormonal regulator of mineral metabolism

摘要

We have isolated a human cDNA clone en- coding the mammalian homolog of stanniocalcin (STC), a calcium- and phosphate-regulating hormone that was first described in fishes where it functions in preventing hypercal- cemia. STC has a unique amino acid sequence and, until now, has remained one of the few polypeptide hormones never described in higher vertebrates.