GROWTH HORMONE EXPRESSION INHIBITOR, ADULT GROWTH HORMONE SECRETION FAILURE MODEL NONHUMAN ANIMAL, PRODUCTION METHOD OF ADULT GROWTH HORMONE SECRETION FAILURE MODEL NONHUMAN ANIMAL, FUNCTIONAL REGULATOR OF BROWN FAT CELL, FAT STORAGE DISEASE MODEL NONHUMAN ANIMAL, AND PRODUCTION METHOD OF FAT STORAGE DISEASE MODEL NONHUMAN ANIMAL

摘要

PROBLEM TO BE SOLVED: To provide a growth hormone expression inhibitor and the like which can reproduce pathological conditions caused by adult growth hormone secretion failure in various animals more conveniently.SOLUTION: The growth hormone expression inhibitor contains a polypeptide selected from the group consisting of (a) a polypeptide composed of an amino acid sequence represented by any of sequence ID numbers 1-8, (b) a polypeptide composed of an amino acid sequence in which one or some amino acids are deleted, substituted, or added in the amino acid sequence represented by any of sequence ID numbers 1-8, (c) a polypeptide composed of an amino acid sequence having 30% or more sequence identity to the amino acid sequence represented by any of sequence ID numbers 1-8; and at least either one of any of the (a)-(c) polypeptides, or an expression vector comprising a nucleic acid composed of a base sequence encoding a precursor protein of the polypeptide.