Aminolevulinate photodynamic therapy (ALA-PDT) for giant seborrheic keratosis of the head: A case report

摘要

Although Seborrheic keratosis of the head is very common, giant seborrheic keratosis is rare. This condition should be distinguished from other skin malignant tumors by skin histopathological and immunohistochemistry.We report a case of a 61-year-old woman who presented with a large, dark-brown, well-demarcated plaque on the top of her head of seven years duration which then progressed rapidly for one year. Dermoscopy, histopathological examination and immunohistochemical examination were performed successively. The patient was diagnosed with seborrheic keratosis. She was treated with aminolevulinate photodynamic therapy (ALA-PDT). The lesion was reduced and thinned following treatment. Therefore, we believe that ALA-PDT is a choice for the treatment of giant seborrheic keratosis, especially in some special areas that affect appearance and function.