Mélanomes primitifs des muqueuses nasosinusiennes: à propos de cinq cas

摘要

Primitive melanomas of the nasosinusal mucosa are rare. They only represent 0.5 to 2% of melanoma and usually cause unilateral nasal obstruction and nasal bleeding. The diagnosis is histological, achieved via immunohistochemistry analysis. Their prognosis remains poor in spite of surgical treatment associated with post-surgical chemoradiotherapy. Our objective is to discuss the epidemiological, clinical and pathological data relating to primary melanoma of the nasosinusal mucosa and to study their development potential and prognostic features.