Haematological Study on the Fungicide Ziram Induced Acute, Subacute and Subchronic Toxicity in Broiler Chickens

摘要

The present work was conducted to elucidate the haematological changes in broiler chickens after Ziram intoxication. For this study, 150 apparently healthy broiler chicks were reared up to 2 weeks of age and randomly allocated to four groups, i.e. acute (N=10), sub-acute (N=20), sub-chronic (N=90) and control (N=30). Toxicity was induced following a single oral dose of Ziram @ 100mg/kg body weight for acute intoxication; 5 mg/kg body weight per day for 20 days in case of sub-acute group and 1 mg/kg body weight per day for the study period of 90 days in case of sub-chronic intoxication. At the end of the experimental period the investigations revealed significant decrease in haemoglobin concentration, packed cell volume, total erythrocyte count and leucocytosis with heterophilia leading to clinical anaemia.