SYNTHESIS OF VINCA ALKALOIDS AND RELATED COMPOUNDS .79. AN INTRIGUING RETRO DIELS-ALDER REACTION

摘要

The dimerization production of criocerine (1) are different (2 or 3) depending on whether the reaction is carried out in acetic acid or trifluoroacetic acid. The highly strained product 3 rearranges spontaneously through a retro Diels-Alder reaction. All structures involved were thoroughly investigated by NMR spectroscopic methods. [References: 9]