Gene expression of fas, soluble and fas-li- gand in thyroid tissues and thyrocytes from pa- tients with graves' disease

摘要

Conclu- sion Gene expression of Fas, sFas and Fas-L showed abnormality in both thyroid tissues and thyro- cytes from GD. The increased production of sFas might be involved in the hyperplasia of thryoid gland. Objective To investigate Fas, soluble Fas(sFas)and Fas-ligang(Fas-L) Gene expression in thyroid tissues and thyrocytes from patients with Graves disease(GD)and to find The interrelationship between apoptosis and pathogenesis of GD. Methods Thyriod tissues were ob- Tained form 7 GD patients and 3 healthy subjects who died accidentally.