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The effects of the tilt angle of a bileaflet mechanical heart valve on blood flow and leaflet motion

机译:双叶机械心脏瓣膜倾斜角对血流和小叶运动的影响

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Diseased heart valves can be replaced with bileaflet mechanical heart valves (BMHVs), which may be affected by complications such as hemolysis, platelet activation and device failure. These complications are closely related to the characteristics of blood flow through mechanical valves and leaflet dynamics, and can become worse with tilted implantation of BMHVs. This study simulated the interactions of blood flow and leaflet motion for BMHVs implanted at different tilt angles. A fluid-structure interaction (FSI) method was employed to solve the problems of blood flow and leaflet motion interactively. A validation of the present numerical methods was performed against data produced in a previous work, indicating that the method presented in this study is reliable. Our results reveal detailed blood flow and leaflet motion in an aorta caused by the systole and diastole of the ventricle. As the tilt angle increased, the degree of asymmetry of blood flow and the time delay in the motions of the two different leaflets also increased, which may cause worsening of complications.
机译:患病的心脏瓣膜可以用双叶机械心脏瓣膜(BMHV)代替,它可能会受到诸如溶血,血小板活化和设备故障等并发症的影响。这些并发症与通过机械瓣膜的血流特征和小叶动力学密切相关,并且随着BMHV的倾斜植入而变得更加严重。这项研究模拟了植入不同倾斜角度的BMHV的血流和小叶运动的相互作用。流体-结构相互作用(FSI)方法被用来交互地解决血液流动和小叶运动的问题。针对先前工作中产生的数据对当前数值方法进行了验证,这表明本研究中提出的方法是可靠的。我们的研究结果揭示了由心室的收缩和舒张引起的详细的主动脉血流量和小叶运动。随着倾斜角的增加,血流的不对称程度和两个不同小叶的运动中的时间延迟也增加,这可能导致并发症恶化。

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