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The types of scientific information and technologies acquired from university-industry relationships in the Japanese pharmaceutical industry - an empirical study from 1980 to 2012

机译:从日本制药业的大学与行业关系中获得的科学信息和技术的类型-1980年至2012年的一项实证研究

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This study investigated the types of scientific knowledge and technologies acquired by Japanese pharmaceutical companies through university-industry (U-I) collaboration over a period of 30 years. Although academic research has made significant contributions to new drug discovery, there has been no detailed examination of the types of scientific information and technologies provided by U-I collaboration. This study showed that the most frequently acquired scientific information concerned basic biological mechanisms, followed by medicinal chemistry and pharmacology knowledge. As regards technologies, academic institutions frequently provided drug candidates and lead compounds in addition to research tools and assays. The analysis of time trends for these acquisitions reveals the existence of both: 1) scientific information and technology that were consistently acquired over the 30 years; 2) technologies that were transiently acquired at a particular time period. The implications of these findings for the effective management practice of U-I collaboration in drug discovery and development are discussed.
机译:这项研究调查了日本制药公司在30年间通过大学与行业(U-I)合作获得的科学知识和技术的类型。尽管学术研究为新药发现做出了重大贡献,但尚未对U-I合作提供的科学信息和技术类型进行详细检查。这项研究表明,最常获得的科学信息涉及基本生物学机制,其次是药物化学和药理知识。关于技术,学术机构除了研究工具和测定法外,还经常提供候选药物和先导化合物。对这些收购的时间趋势的分析揭示了两者的存在:1)在过去30年中不断获得的科学信息和技术; 2)在特定时间段内暂时获得的技术。讨论了这些发现对药物发现和开发中U-I合作的有效管理实践的意义。

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