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Effectiveness of Fuzzy Classifier Rules in Capturing Correlations between Genes

机译:模糊分类规则在捕获基因间相关性中的有效性

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摘要

In this article, we take advantage of using fuzzy classifier rules to capture the correlations between genes. The main motivation to conduct this study is that a fuzzy classifier rule is essentially an 搃f-then?rule that contains linguistic terms to represent the feature values. This representation of a rule that demonstrates the correlations among the genes is very simple to understand and interpret for domain experts. In our proposed gene selection procedure, instead of measuring the effectiveness of every single gene for building the classifier model, we incorporate the impotence of a gene correlation with other existing genes in the process of gene selection. That is, we reject a gene if it is not in a significant correlation with other genes in the dataset. Furthermore, in order to improve the reliability of our approach, we repeat the process several times in our experiments, and the genes reported as the result are the genes selected in most experiments.
机译:在本文中,我们利用了模糊分类器规则来捕获基因之间的相关性。进行这项研究的主要动机是,模糊分类器规则本质上是一个包含语言术语以表示特征值的“ f-then”规则。证明基因之间相关性的规则表示对于领域专家来说非常容易理解和解释。在我们提出的基因选择程序中,我们没有测量建立一个分类器模型的每个单个基因的有效性,而是在基因选择过程中结合了与其他现有基因的基因相关性。也就是说,如果某个基因与数据集中的其他基因没有显着相关性,我们将拒绝该基因。此外,为了提高方法的可靠性,我们在实验中重复了几次该过程,结果报告的基因是大多数实验中选择的基因。

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