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首页> 外文期刊>International Archives of Occupational and Environmental Health >Transplacental exposure of neonates to perfluorooctanesulfonate and perfluorooctanoate: a pilot study
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Transplacental exposure of neonates to perfluorooctanesulfonate and perfluorooctanoate: a pilot study

机译:新生儿经胎盘暴露于全氟辛烷磺酸和全氟辛酸的先导研究

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摘要

Perfluorooctanesulfonate (PFOS) and perfluorooctanoate (PFOA) can be released of perfluorinated compounds by biotic and/or metabolic decomposition. Due to their ubiquitous occurrence, persistence and bioaccumulative properties they can be found in blood of the general population all over the world. In animal studies PFOS and PFOA provoked cancer and showed developmental toxic potential besides other adverse health effects. On the basis of the comparison of maternal and umbilical cord plasma sample pairs we wanted to examine whether infants are exposed to PFOS and PFOA via their mothers’ blood.
机译:全氟辛烷磺酸(PFOS)和全氟辛酸酯(PFOA)可以通过生物和/或代谢分解而从全氟化合物中释放出来。由于它们的普遍存在,持久性和生物蓄积性,它们可以在全世界普通人群的血液中发现。在动物研究中,全氟辛烷磺酸和全氟辛酸引起了癌症,并显示出发展毒性的潜力,以及其他不利健康影响。在比较母体和脐带血浆样本对的基础上,我们希望检查婴儿是否通过母亲的血液暴露于PFOS和PFOA。

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  • 作者单位

    Institute and Outpatient Clinic of Occupational Social and Environmental Medicine University of Erlangen-Nuremberg Schillerstrasse 25 91054 Erlangen Germany;

    Institute and Outpatient Clinic of Occupational Social and Environmental Medicine University of Erlangen-Nuremberg Schillerstrasse 25 91054 Erlangen Germany;

    Clinic and Outpatient Clinic for Gynaecology University of Erlangen-Nuremberg Erlangen Germany;

    Clinic and Outpatient Clinic for Gynaecology University of Erlangen-Nuremberg Erlangen Germany;

    Institute and Outpatient Clinic of Occupational Social and Environmental Medicine University of Erlangen-Nuremberg Schillerstrasse 25 91054 Erlangen Germany;

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  • 原文格式 PDF
  • 正文语种 eng
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  • 关键词

    Perfluorooctanesulfonate (PFOS); Perfluorooctanoate (PFOA); Umbilical cord blood; Neonates; Placental barrier;

    机译:全氟辛烷磺酸(PFOS);全氟辛酸酯(PFOA);脐带血;新生儿;胎盘屏障;

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