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Evanescent microwaves: a novel super-resolution noncontact nondestructive imaging technique for biological applications

机译:van逝微波:一种用于生物应用的新型超分辨率非接触式非破坏性成像技术

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Scanning tunneling microscopes (STM) and atomic force microscopes (AFM) are used to study biological materials. These methods, often capable of achieving atomic resolutions, reveal fascinating information regarding the inner workings of these materials. However, both STM and AFM require physical contact to the specimen. In the case of STM the specimen needs to be conducting as well. Here we introduce a new method for imaging biological materials through air or a suitable liquid using decaying or evanescent fields at the tip of a properly designed microwave resonator. This novel method involves the use of an evanescent microwave probe (EMP) and it is capable of imaging a variety of nonuniformities in biological materials including conductivity, permittivity, and density variations. EMP is a noncontact and nondestructive sensor and it does not require conducting specimens. Its spatial resolution is currently around 0.4 /spl mu/m at 1 GHz. We have used this probe to map nonuniformities in a variety of materials including metals, semiconductors, insulators, and biological and botanical samples. Here we discuss applications of EMP imaging in bone, teeth, botanical, and agricultural specimens.
机译:扫描隧道显微镜(STM)和原子力显微镜(AFM)用于研究生物材料。这些方法通常能够实现原子分辨率,可揭示有关这些材料内部工作原理的有趣信息。但是,STM和AFM都需要与样品物理接触。在STM的情况下,样品也需要导电。在这里,我们介绍了一种新方法,该方法通过在适当设计的微波谐振器尖端处的衰减场或渐逝场,通过空气或合适的液体对生物材料进行成像。这种新方法涉及使用消逝微波探针(EMP),并且能够对生物材料中的各种不均匀性进行成像,包括电导率,介电常数和密度变化。 EMP是一种非接触式且无损的传感器,不需要导电样品。目前,其空间分辨率在1 GHz时约为0.4 / spl mu / m。我们已经使用该探针绘制了包括金属,半导体,绝缘体以及生物和植物样品在内的多种材料中的不均匀性图。在这里,我们讨论EMP成像在骨骼,牙齿,植物和农业标本中的应用。

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