Desmosomal protein gene mutations in patients withidiopathic dilated cardiomyopathy undergoing cardiactransplantation: a clinicopathological study

摘要

Backgroud Idiopathic dilated cardiomyopathy (DCM) is the most frequent indication for orthotopic heart transplantation. It has been suggested that mutations in genes encoding desmosomal proteins, more typically associated with arrhythmogenic right ventricular cardiomyopathy, are a cause of DCM.