動物用医薬品等通知一斉試騳法の加工食品への適用

摘要

加工食品は複数の素材から製造されている場合が多く，rn原料まで追跡することは非常に困難である．また，加工食rn品は主に保存性を高めるため，大部分が加熱，乾燥，加rn糖，加塩，レトルトなどの加工が施されており，このようrnな加工処理による成分変化によって，生鮮食品以上にマトrnリックスが複雑であることも多い．多くの加工食品の適法rn性を迅速に確認するためには，原料由来の成分（マトリッrnクス）の影響をできる限り排除しうる高い選択性を保有rnし，迅速かっ多成分を一斉に検査できる分析法が望ましいrnが，加工食品の分析法に関する知見は極めて少ない．%To ensure the safety of processed foods, we developed a method for simultaneous determination of residual veterinary drugs in some processed foods. Eighty-nine compounds were selected for the analysis based on reports of illegal use of the veterinary drugs and our research information. In our LC/MS/MS system, an Atlantis C_(18) column, which could separate a wide range of compounds, was used with a gradient system of 0.1% formic acid-acetonitrile containing 0.1% formic acid as the mobile phase. Sharp and symmetrical peaks with sufficient signal intensity were obtained. In this system, the recovery rates of detected veterinary drugs in processed foods were mostly in the range of 60-120%. Therefore, it is considered that this method is suitable for screening of residual veterinary drugs in processed foods.