18F-FLT PET/CT as an imaging tool for early prediction of pathological response in patients with locally advanced breast cancer treated with neoadjuvant chemotherapy: a pilot study

Flavio Crippa; Roberto Agresti; Marco Sandri; Gabriella Mariani; Barbara Padovano; Alessandra Alessi; Giulia Bianchi; Emilio Bombardieri; Ilaria Maugeri; Mario Rampa; Maria Luisa Carcangiu; Giovanna Trecate; Claudio Pascali; Anna Bogni; Gabriele Martelli; Filippo de Braud

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18F-FLT PET/CT as an imaging tool for early prediction of pathological response in patients with locally advanced breast cancer treated with neoadjuvant chemotherapy: a pilot study

机译：18F-FLT PET / CT作为影像学工具，可早期预测接受新辅助化疗的局部晚期乳腺癌患者的病理反应

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摘要

Purpose We evaluated whether 18F-3′-deoxy-3′-fluorothymidine positron emission tomography (FLT PET) can predict the final postoperative histopathological response in primary breast cancer after the first cycle of neoadjuvant chemotherapy (NCT).

机译：目的我们评估了18F-3'-脱氧-3'-氟胸苷正电子发射断层显像（FLT PET）是否可以预测新辅助化疗（NCT）的第一个周期后原发性乳腺癌的最终术后组织病理学反应。

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来源
《European Journal of Nuclear Medicine and Molecular Imaging》 |2015年第6期|818-830|共13页
作者
Flavio Crippa; Roberto Agresti; Marco Sandri; Gabriella Mariani; Barbara Padovano; Alessandra Alessi; Giulia Bianchi; Emilio Bombardieri; Ilaria Maugeri; Mario Rampa; Maria Luisa Carcangiu; Giovanna Trecate; Claudio Pascali; Anna Bogni; Gabriele Martelli; Filippo de Braud;
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作者单位

Nuclear Medicine Unit Fondazione IRCCS Istituto Nazionale dei Tumori – Milan (Italy)">(1);

Breast Surgery Unit Fondazione IRCCS Istituto Nazionale dei Tumori – Milan (Italy)">(2);

Molecular Targeting Unit Fondazione IRCCS Istituto Nazionale dei Tumori – Milan (Italy)">(3);

Medical Oncology Unit Fondazione IRCCS Istituto Nazionale dei Tumori – Milan (Italy)">(4);

Nuclear Medicine Unit Fondazione IRCCS Istituto Nazionale dei Tumori – Milan (Italy)">(1);

Nuclear Medicine Unit Fondazione IRCCS Istituto Nazionale dei Tumori – Milan (Italy)">(1);

Medical Oncology Unit Fondazione IRCCS Istituto Nazionale dei Tumori – Milan (Italy)">(4);

Nuclear Medicine Unit Fondazione IRCCS Istituto Nazionale dei Tumori – Milan (Italy)">(1);

Breast Surgery Unit Fondazione IRCCS Istituto Nazionale dei Tumori – Milan (Italy)">(2);

Breast Surgery Unit Fondazione IRCCS Istituto Nazionale dei Tumori – Milan (Italy)">(2);

Pathology Unit Fondazione IRCCS Istituto Nazionale dei Tumori – Milan (Italy)">(5);

Radiology-RMI Unit Fondazione IRCCS Istituto Nazionale dei Tumori – Milan (Italy)">(6);

Nuclear Medicine Unit Fondazione IRCCS Istituto Nazionale dei Tumori – Milan (Italy)">(1);

Nuclear Medicine Unit Fondazione IRCCS Istituto Nazionale dei Tumori – Milan (Italy)">(1);

Breast Surgery Unit Fondazione IRCCS Istituto Nazionale dei Tumori – Milan (Italy)">(2);

Medical Oncology Unit Fondazione IRCCS Istituto Nazionale dei Tumori – Milan (Italy)">(4);

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正文语种 eng
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关键词
Breast cancer; Neoadjuvant chemotherapy; FLT PET; Pathological response predictive rule;

机译：乳腺癌;新辅助化疗;FLT PET;病理反应预测规则;

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专利

1. 1?F-FLT PET/CT as an imaging tool for early prediction of pathological response in patients with locally advanced breast cancer treated with neoadjuvant chemotherapy: a pilot study. [J] . Flavio Crippa, Roberto Agresti, Marco Sandri, European Journal of Nuclear Medicine and Molecular Imaging . 2015,第6期

机译：1？F-FLT PET / CT作为影像学工具，可以早期预测接受新辅助化疗的局部晚期乳腺癌患者的病理反应：一项先导研究。
2. The Value of F-18-FDG PET/CT Imaging Combined With Pretherapeutic Ki67 for Early Prediction of Pathologic Response After Neoadjuvant Chemotherapy in Locally Advanced Breast Cancer [J] . Luo Jurui, Zhou Zhirui, Yang Zhaozhi, Medicine. . 2016,第8期

机译：F-18-FDG PET / CT成像与治疗前Ki67结合对局部晚期乳腺癌新辅助化疗后病理反应的早期预测价值
3. Dynamic contrast-enhanced MRI texture analysis for pretreatment prediction of clinical and pathological response to neoadjuvant chemotherapy in patients with locally advanced breast cancer [J] . Jose R. Teruel, Mariann G. Heldahl, P?l E. Goa, NMR in biomedicine . 2014,第8期

机译：动态对比增强MRI纹理分析用于局部晚期乳腺癌患者对新辅助化疗的临床和病理反应的预处理预测
4. Prediction of Pathological Complete Response to Neoadjuvant Chemotherapy in Breast Cancer Using Deep Learning with Integrative Imaging, Molecular and Demographic Data [C] . Hongyi Duanmu, Pauline Boning Huang, Srinidhi Brahmavar, International Conference on Medical Image Computing and Computer-Assisted Intervention . 2020

机译：利用综合成像，分子和人口统计数据预测对乳腺癌新辅助化疗的病理完全反应
5. Coregistration of serial breast MR studies for augmenting neoadjuvant chemotherapy response evaluation in breast cancer patients. [D] . Chittineni, Ruparani. 2008

机译：增强乳腺癌患者新系列辅助化疗反应评估的系列乳房MR研究的核心。
6. The Value of 18F-FDG PET/CT Imaging Combined With Pretherapeutic Ki67 for Early Prediction of Pathologic Response After Neoadjuvant Chemotherapy in Locally Advanced Breast Cancer [O] . Jurui Luo, Zhirui Zhou, Zhaozhi Yang, -1

机译：18F-FDG PET / CT成像与治疗前Ki67结合对局部晚期乳腺癌新辅助化疗后病理反应的早期预测价值
7. The Value of 18F-FDG PET/CT Imaging Combined With Pretherapeutic Ki67 for Early Prediction of Pathologic Response After Neoadjuvant Chemotherapy in Locally Advanced Breast Cancer [O] . Jurui Luo, Zhirui Zhou, Zhaozhi Yang, 2016

机译：18F-FDG PET / CT成像的价值与Pretherapeutic Ki67联合用于局部晚期乳腺癌新辅助化疗后病理反应的早期预测

18F-FLT PET/CT as an imaging tool for early prediction of pathological response in patients with locally advanced breast cancer treated with neoadjuvant chemotherapy: a pilot study

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