Comparison of three marine screening tests and four Oslo and paris commission procedures to evaluate toxicity of offshore chemicals

摘要

the results from the screening toxicity tests Artemia salina, Microtox~R, and Mitochondria RET test were compared with those obtained from OSPAR (Oslo and Paris Commissions)-authorized procedures for testing of offshore chemicals (Skele- tonema costatum, Acartia tonsa, Abra alba, and Corophium volutator). In this study 82 test substances (26 non-water soluble) were included. The Microtox test was found to e the most sensitive of the three screening tests. Microtox and Mitochondria RET test results showed good correlation with results from Acartia and Skeletonema testing, and it was concluded that the Microtox was a suitable screening test as a base for assessment of further testing, especially regarding water-soluble chemicals.