Comment on 'Assessing Aromatic-Hydrocarbon Toxicity to Fish Early Life Stages Using Passive-Dosing Methods and Target-Lipid and Chemical-Activity Models'

摘要

Recently, Butler and co-workers reported a comprehensive zebrafish early life stage toxicity study of aromatic hydro-carbons：~1 Passive dosing was applied to tightly control the exposure of several hydrophobic organic chemicals in 30 day chronic toxicity tests, and constant exposure concentrations were carefully confirmed by analytical measurements. The embryo acute toxicity of phenanthrene in this recent study~1 (LC_(50) of 334 μg/L) agreed very well with another recent short-term study with the same test organism, passive dosing system and exposure time (LC_(50) of 310 µg/L~2).