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Levels and profiles of PCDD/Fs, PCBs in mothers' milk in Shenzhen of China: Estimation of breast-fed infants' intakes

机译:中国深圳母乳中PCDD / Fs,PCBs的水平和概况:估计母乳喂养婴儿的摄入量

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摘要

Sixty breast milk samples were collected in Shenzhen, China from July to November in 2007. The samples were analyzed of the concentrations of polychlorinated dibenzo-p-dioxins (PCDDs), polychlorinated dibenzofurans (PCDFs) and polychlorinated biphenyls (PCBs). The range of upper-bound for ∑TEQ-(PCDD/Fs+PCBs) in the samples was 4.10-35.3 pg TEQ g~(-1) lipid (median: 10.6pgTEQg~(-1) lipid; mean: 11.9pgTEQg~(-1) lipid). The levels of the measured contaminants in the breast milk had significant correlations with the length of inhabitation period in Shenzhen (r=0.487, p<0.05 for PCDD/Fs, r = 0.431, p<0.05 for PCBs and r = 0.478, p<0.05 for ∑TEQ.-(PCDD/Fs+PCBs)), and the consumption rate of fish (r = 0.366, p<0.05 for PCDD/Fs, r = 0.486, p<0.05 for PCBs and r = 0.416, p<0.05 for ∑TEQ.-(PCDD/Fs+PCBs)), respectively. Moreover, significant positive correlations were also detected between the participant's age (r=0.305, p < 0.05 for ∑ TEQ-PCBs and r = 0.275, p<0.05 for ∑TEQ.-(PCDD/Fs+PCBs)) and the body burdens of these contaminants respectively. It is estimated that the daily intake (EDI) of the sum of PCDD/Fs and DL-PCBs by the breast-fed infants was 5.60-161 pg TEQ kg~(-1) bw per day (mean: 48.2 pg TEQ kg~(-1) bw per day; median: 42.2 pg TEQ kg~(-1) bw per day). The result showed that both the body burdens of PCDD/Fs and PCBs of the recruit population and the calculated EDI of the breast-fed infants were higher than those in the non-exposed areas in mainland China. This suggests that continuous surveillance on PCDD/Fs and PCBs levels in human milk is critical to more precisely evaluate the human health risk posed by the negative environmental impact in Shenzhen in the future.
机译:2007年7月至11月,在中国深圳收集了60份母乳样品。分析了这些样品中多氯二苯并对二恶英(PCDDs),多氯二苯并呋喃(PCDFs)和多氯联苯(PCBs)的浓度。样品中∑TEQ-(PCDD / Fs + PCBs)的上限范围是4.10-35.3 pg TEQ g〜(-1)脂质(中位数:10.6pgTEQg〜(-1)脂质;平均值:11.9pgTEQg〜 (-1)脂质)。在深圳,母乳中的污染物含量与居住时间长短有显着相关性(r = 0.487,对于PCDD / Fs,p <0.05,r = 0.431,对于PCBs,p <0.05,r = 0.478,p < ∑TEQ .-((PCDD / Fs + PCBs)为0.05),鱼的消耗率(r = 0.366,PCDD / Fs为p <0.05,r = 0.486,对于PCBs为p <0.05,r = 0.416,p < ∑TEQ .-((PCDD / Fs + PCBs))分别为0.05。此外,在参与者的年龄(r = 0.305,对于∑TEQ-PCBs,r <0.275,p = 0.05,对于∑TEQ .-(PCDD / Fs + PCBs),p = 0.05)之间也发现了显着的正相关。这些污染物分别。据估计,母乳喂养的婴儿每天PCDD / Fs和DL-PCBs的总摄入量(EDI)为5.60-161 pg TEQ kg〜(-1)bw(平均:48.2 pg TEQ kg〜 (-1)bw每天;中位数:42.2 pg TEQ kg〜(-1)bw每天)。结果表明,新兵的PCDD / Fs和PCBs的身体负担以及母乳喂养婴儿的EDI计算值均高于中国大陆非暴露地区。这表明,连续监测母乳中PCDD / Fs和PCBs的水平对于更准确地评估未来深圳负面环境影响所带来的人类健康风险至关重要。

著录项

  • 来源
    《Environment international》 |2012年第2012期|p.47-52|共6页
  • 作者单位

    Department of POPs Lab. Shenzhen Center for Disease Control and Prevention. No. 21. 1st Road Tianbei. Luohu District. Shenzhen, Guangdong 518020, PR China,North Sichuan Medical College, Nanchong, Sichuan, 637000, PR China;

    Department of POPs Lab. Shenzhen Center for Disease Control and Prevention. No. 21. 1st Road Tianbei. Luohu District. Shenzhen, Guangdong 518020, PR China;

    West China University of Medical Sciences, Sichuan University, Chengdu, Sichuan, 610041. PR China;

    Department of POPs Lab. Shenzhen Center for Disease Control and Prevention. No. 21. 1st Road Tianbei. Luohu District. Shenzhen, Guangdong 518020, PR China;

    Department of POPs Lab. Shenzhen Center for Disease Control and Prevention. No. 21. 1st Road Tianbei. Luohu District. Shenzhen, Guangdong 518020, PR China;

    Department of POPs Lab. Shenzhen Center for Disease Control and Prevention. No. 21. 1st Road Tianbei. Luohu District. Shenzhen, Guangdong 518020, PR China;

    Department of POPs Lab. Shenzhen Center for Disease Control and Prevention. No. 21. 1st Road Tianbei. Luohu District. Shenzhen, Guangdong 518020, PR China;

    Department of POPs Lab. Shenzhen Center for Disease Control and Prevention. No. 21. 1st Road Tianbei. Luohu District. Shenzhen, Guangdong 518020, PR China;

  • 收录信息 美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《化学文摘》(CA);
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    body burden; polychlorinated dibenzo-p-dioxins; polychlorinated dibenzofurans; polychlorinated biphenyls; estimated daily intakes (EDI); human breast milk;

    机译:身体负担;多氯二苯并对二恶英;多氯二苯并呋喃;多氯联苯;估计每日摄入量(EDI);人母乳;

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