ZEB2 Promotes the Metastasis of Gastric Cancer and Modulates Epithelial Mesenchymal Transition of Gastric Cancer Cells

Ying-Huan Dai; Ya-Ping Tang; Hong-Yi Zhu; Liang Lv; Yi Chu; Yu-Qian Zhou; Ji-Rong Huo

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ZEB2 Promotes the Metastasis of Gastric Cancer and Modulates Epithelial Mesenchymal Transition of Gastric Cancer Cells

机译：ZEB2促进胃癌的转移，并调节胃癌细胞的上皮间质转化。

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摘要

Invasion and metastasis are the hallmarks of advanced gastric cancer progression. Therefore, it is urgent to overcome metastasis in order to improve the survival of gastric cancer patients.

机译：侵袭和转移是晚期胃癌进展的标志。因此，迫切需要克服转移以提高胃癌患者的生存率。

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来源
《Digestive Diseases and Sciences》 |2012年第5期|p.1253-1260|共8页
作者
Ying-Huan Dai; Ya-Ping Tang; Hong-Yi Zhu; Liang Lv; Yi Chu; Yu-Qian Zhou; Ji-Rong Huo;
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作者单位

Department of Gastroenterology, Second Xiangya Hospital of Central South University, Changsha, 410011, Hunan Province, China;

Department of Gastroenterology, Second Xiangya Hospital of Central South University, Changsha, 410011, Hunan Province, China;

Department of Gastroenterology, Second Xiangya Hospital of Central South University, Changsha, 410011, Hunan Province, China;

Department of Gastroenterology, Second Xiangya Hospital of Central South University, Changsha, 410011, Hunan Province, China;

Department of Gastroenterology, Second Xiangya Hospital of Central South University, Changsha, 410011, Hunan Province, China;

Department of Gastroenterology, Second Xiangya Hospital of Central South University, Changsha, 410011, Hunan Province, China;

Department of Gastroenterology, Second Xiangya Hospital of Central South University, Changsha, 410011, Hunan Province, China;

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正文语种 eng
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关键词
ZEB2; Gastric cancer; Migration; Invasion; Epithelial-mesenchymal transition;

机译：ZEB2;胃癌;迁移;侵袭;上皮-间质转化;

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专利

1. ZEB2 promotes the metastasis of gastric cancer and modulates epithelial mesenchymal transition of gastric cancer cells. [J] . Ying-Huan Dai, Ya-Ping Tang, Hong-Yi Zhu, Digestive Diseases and Sciences . 2012,第5期

机译：ZEB2促进胃癌的转移并调节胃癌细胞的上皮间质转化。
2. HOXB8 promotes tumor metastasis and the epithelial-mesenchymal transition via ZEB2 targets in gastric cancer [J] . Ding Wen-Jin, Zhou Min, Chen Mei-Mei, Journal of Cancer Research and Clinical Oncology . 2017,第3期

机译：HoxB8促进肿瘤转移和通过胃癌中的靶向靶向靶向血管性能转变
3. Src promotes EGF‐induced epithelial‐to‐mesenchymal transition and migration in gastric cancer cells by upregulating ZEB1 and ZEB2 through AKT [J] . Zhao Lei, Li Xin, Song Na, Cell biology international. . 2018,第3期

机译：通过将Zeb1和Zeb2通过Akt促进EGF诱导的EGF诱导的上皮 - 间充质转变和迁移在胃癌细胞中
4. Engineered Nano-Clay Based 3D Tumor Model as a Test-Bed to evaluate Mesenchymal to Epithelial Transition #(MET) in Prostate Cancer Metastasis [C] . MD Shahjahan Molla, Dinesh Katti, Kalpana Katti Society for Biomaterials annual meeting and exposition . 2017

机译：设计基于纳米粘土的3D肿瘤模型作为测试床，以评估前列腺癌转移中的间质向上皮转变＃（MET）
5. Identifying Novel Inhibitors of Epithelial to Mesenchymal Transition (EMT) for Targeting Pancreatic Cancer Metastasis and Cancer Stem Cells [D] . Polireddy, Kishore. 2015

机译：确定靶向胰腺癌转移和癌症干细胞的新型上皮间质转化抑制剂（EMT）
6. Honokiol Suppresses Renal Cancer Cells’ Metastasis via Dual-Blocking Epithelial-Mesenchymal Transition and Cancer Stem Cell Properties through Modulating miR-141/ZEB2 Signaling [O] . Weidong Li, Qian Wang, Qiaozhen Su, 2014

机译：厚朴酚通过调节miR-141 / ZEB2信号传导通过双重阻断的上皮-间质转化和癌症干细胞特性抑制肾癌细胞的转移
7. Honokiol Suppresses Renal Cancer Cells’ Metastasis via Dual-Blocking Epithelial-Mesenchymal Transition and Cancer Stem Cell Properties through Modulating miR-141/ZEB2 Signaling [O] . Weidong Li, Qian Wang, Qiaozhen Su, 2014

机译：通过调节miR-141 / Zeb2信号传导，通过双阻断上皮 - 间充质转换和癌症干细胞性能抑制肾癌细胞的转移

ZEB2 Promotes the Metastasis of Gastric Cancer and Modulates Epithelial Mesenchymal Transition of Gastric Cancer Cells

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